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A Goldilocks zone of DNA flexibility defines stable yet plastic nucleosomes, tuned by histone chemistry https://www.biorxiv.org/content/10.64898/2026.02.16.706184v1

4mo

How do DNA sequence and histone chemistry tune nucleosome stability and plasticity? Check out our latest work to find out. Now available on bioRxiv! www.biorxiv.org/content/10.6... @juliamaristany.bsky.social @janhuemar.bsky.social @rcollepardo.bsky.social Share with your colleagues!! ⬇️⬇️⬇️

4mo

bioRxiv Biophysics

New preprint alert! Very proud of this work, lots of hard work that turned into a really cool story! This was my first chance to step into a senior role, but most importantly, it means far more to me than just the science. You should always say yes to new projects. www.biorxiv.org/content/10.6...

Congratulations to @janhuemar.bsky.social (JRF at Catz since 2023) who is part of an international team of scientists responsible for a long-awaited visualisation of liquid droplets forming inside a cell known as condensates, key for processes such as DNA repair: caths.cam.ac.uk/cond... @cam.ac.uk

6mo

4mo

6mo

Super excited to share that our paper is now out in @science.org. Lots of work, but also lots of fun getting this out. Be sure to check it out! www.science.org/doi/10.1126/... Also, follow: @huabin-zhou.bsky.social @juliamaristany.bsky.social @kieran-russell.bsky.social @rcollepardo.bsky.social

New paper alert from the group!! 🚨: DNA flexibility tips the balance between stability and plasticity in nucleosomes One of the works from my PhD, co-led alongside @nachper.bsky.social, is finally out! Work from @rcollepardo.bsky.social & @janhuemar.bsky.social ⬇️ www.biorxiv.org/content/10.6... ⬆️

Make sure to check our latest collaboration with @kaitezhang.bsky.social and @vram142.bsky.social. An effort to move towards simulating non-ideal, "in vivo" chromatin, and learning lots about chromatin organisation while doing it! @juliamaristany.bsky.social @rcollepardo.bsky.social

Our work on the linker histone is now out in Science Advances! We show that H1 behaves as a liquid-like glue that helps organize chromatin in living cells. Very happy to have worked together with @kazu-maeshima.bsky.social and @masaashimazoe.bsky.social

My first, first author paper is now on #ScienceAdvances ! Linker histone H1 is a liquid-like "glue" condensing chromatin, which revises textbooks! 📖✨ science.org/doi/10.1126/sc… Huge thanks to @kazu-maeshima.bsky.social , for supervision. Amazing collab with @rcollepardo.bsky.social ’s group! 1/

Ignacio Perez

4mo

23h

2mo

Jan Huertas

Julia Maristany

Masa A. Shimazoe

St Catharine's College

Very excited to present OpenCGChromatin🔥🔥🔥 A new coarse-grained model that probes full chromatin condensates at near-atomistic resolution to reveal the molecular regulation of chromatin structure and phase separation Brilliantly led by @kieran-russell.bsky.social, with the Rosen and Orozco groups

7mo