Super excited to share that our paper is now out in @science.org. Lots of work, but also lots of fun getting this out.
Be sure to check it out!
www.science.org/doi/10.1126/...
Also, follow:
@huabin-zhou.bsky.social @juliamaristany.bsky.social @kieran-russell.bsky.social @rcollepardo.bsky.social
The structure and interaction networks of molecules within biomolecular condensates are poorly understood. Using cryo–electron tomography and molecular dynamics simulations, we elucidated the structur...
[2/6] How’d we do it? High-resolution cryo-ET captured chromatin condensates at nanometer detail, while simulations brought the histone tails and nucleosome dynamics to life. Together, these tools showed how molecular interactions drive mesoscale chromatin behavior.