chemical biology enthusiast & strategist; I make impossible things possible - all before breakfast!
Milka Kostic
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I’m looking to hire a research technician for my lab at Harvard & DFCI, who would primarily work in the wet lab expressing and characterizing designed proteins, starting this summer. A great role for a recent college grad looking for an immersive research experience before grad school.
Congratulations to @nickpolizzi.bsky.social and colleagues! They combine protein structure prediction with prediction of small molecule binding to map a wide range of functional sites on proteins. Way to boost the hunt for targetable (ligandable) sites!
In a new study published in @natmethods.nature.com, @danafarber.bsky.social’s @nickpolizzi.bsky.social uses features from a pretrained neural network to train a logistic regression model, AF2BIND, which could be used for drug discovery and uncovering functional sites in proteins.
➡️ rdcu.be/e7SnX
We are looking to hire an Assistant/Associate Professor interested in creating an innovative (and exciting) program of research in chemical biology, medicinal chemistry, ML/AI, drug discovery - all in the context of cancer biology!
careers.dana-farber.org/job/11813/as...
New paper from @nickpolizzi.bsky.social, Bill Degrado and Bobo Dang showing that de novo designed small molecule binding proteins can bind to the drug and clear it from the circulation in vivo. Read in Nature Biomedical Engineering!
www.nature.com/articles/s41...
