Congratulations to @nickpolizzi.bsky.social and colleagues! They combine protein structure prediction with prediction of small molecule binding to map a wide range of functional sites on proteins. Way to boost the hunt for targetable (ligandable) sites!
Milka Kostic
In a new study published in @natmethods.nature.com, @danafarber.bsky.social’s @nickpolizzi.bsky.social uses features from a pretrained neural network to train a logistic regression model, AF2BIND, which could be used for drug discovery and uncovering functional sites in proteins.
➡️ rdcu.be/e7SnX
