New paper from @nickpolizzi.bsky.social, Bill Degrado and Bobo Dang showing that de novo designed small molecule binding proteins can bind to the drug and clear it from the circulation in vivo. Read in Nature Biomedical Engineering!
www.nature.com/articles/s41...
Cyclic and mirror-image variants of de novo-designed proteins effectively bind and clear small-molecule drugs in vivo in less than 30 min, highlighting the applicability of computational tools to prod...
