Faculty at Emory Human Genetics, periodically cool dad, typical Boston sports fan (sorry), big believer in Dunning-Kruger effect
Michael Epstein
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I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.
Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15)
Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark!
#Postdoc #Epidemiology #StatisticalGenetics #Biostatistics
👉 international.au.dk/about/profil...
Vacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University
RIP, Prince of Darkness. Arguably in the Top 5 of most influential artists of my lifetime
For those interested in studying cell-cell communication, check out our latest methodological work in AJHG where we discuss more powerful and practical techniques for this task. Project was joint effort with @yjingj.bsky.social and led by our incredible trainee Dr. Qile Dai (now at Lilly)
Our new AJHG paper is online. We develop a new TWAS tool that uses local-ancestry information to improve power of gene mapping in admixed samples. Lead author Taylor Head (now at MD Anderson) did a phenomenal job spearheading this work!
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs.
Paper: www.nature.com/articles/s43...
Happy Chrismukkah to all the delightful half-half situations (like me)
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
www.cell.com
Incredible GRC Genetics and Genomics conference line-up this year in Portland, Maine (www.grc.org/human-geneti...). With conference-maxxing sessions that run to 9:30pm!
Submission deadline is June 8th, conference July 6-11th.
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...
I truly thought this man was going to live forever, somehow. RIP, Ozzy, you were metal incarnate for me. news.sky.com/story/ozzy-o...
Happy to see this out w/ @epsteinstatgen.bsky.social and @davecutler.bsky.social (paper: doi.org/10.1093/bioi...)! We tackled the problem of identifying dysregulated pathways (i.e. differentially co-expressed) in gene expression studies. We show that differential co-expression arises ...
🚨New method!
📄CADET: Enhanced transcriptome-wide association analyses in admixed samples using eQTL summary data
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & co
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
CADET is a transcriptome-wide association test for admixed cohorts that leverages
local ancestry information to improve detection of trait-influencing genes. CADET
outperformed existing methods using ...
