So proud to see this story finally out!๐ We added new data since our previous preprintโtransgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short ๐งต and link to the original preprint thread on X๐
www.science.org/doi/10.1126/...
Finally made it.... congratulations all.
Fun thread. Cool work, and make sure to read all the way to the end!
Preprint Alert ๐จ @philcarella.bsky.social lab stepping into TIR-ritory!! Project started by me but finished by talented PhD student @ebkennedy.bsky.social (Please follow her), with contribution from Zhao He and @jonathandgjones.bsky.social We investigated EDS1-dependency of TIR domain. See thread๐
End of April and I got my diploma๐ฅ Now the PhD degree is official! I hope I've mentioned everyone in my acknowledgments, but I still canโt thank you enough for all the support along this journey: ) If anyone's looking for some 400-page light readingโฆ here it is โก๏ธ ueaeprints.uea.ac.uk/id/eprint/10...
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
@khongsamchia.bsky.social
Extremely excited to share the first pre-print from my PhD project in the Carella lab, co-first authored with @khongsamchia.bsky.social ๐ (Thread below โฌ๏ธ)
www.biorxiv.org/content/10.6...
Huge thanks to all co-authors and the #CarellaCapybaras for all the support ๐
Diana Gรณmez De La Cruz
Just published: Breaking the Pattern with AlphaFold: Introducing the Structural Novelty Index
AlphaFold has transformed how we predict protein structures. But sometimes most interesting discoveries come from asking a different question: which proteins break the pattern?
medium.com/p/breaking-t...
www.biorxiv.org
Check out our latest pre-print on the evolution of TIR activity/signalling: www.biorxiv.org/content/10.6...
Hsuan Pai ็ฝๆ
Larry Hunter
The Tattooed Professor
New Preprint in collaboration with GoogleDeepMind: AI-guided discovery of atypical protein assemblies
The @kamounlab.bsky.social discovered an 11-protomer complex thanks to the Structural Novelty Indexโ, a new way to use AlphaFold to find protein assemblies that break the pattern.
KhongSam Chia
Sophien Kamoun
๐ข PDRA Position - Plant Immune Receptor Bioengineering at Imperial College London
๐ฑ Start: Aug 2026 (flexible)
๐งช Wet lab + bioinformatics
๐ Up to 3 years (ERC-funded)
๐ South Kensington, on site
โน๏ธ shorturl.at/VIITk
๐ kourelislab.com
#PlantImmunity #PlantPathology
๐ Share with interested candidates!
Elenor Kennedy
Phil Carella
The Sainsbury Laboratory
The variable wheat stripe rust effector AvrYr7 evades Yr7 recognition through sequence and expression polymorphisms https://www.biorxiv.org/content/10.64898/2026.05.09.724051v1
Artificial intelligence (AI) systems such as AlphaFold have transformed structural biology by enabling accurate prediction of protein structures. However, their capacity to uncover new classes ofโฆ
@khongsamchia.bsky.social
Extremely excited to share the first pre-print from my PhD project in the Carella lab, co-first authored with @khongsamchia.bsky.social ๐ (Thread below โฌ๏ธ)
www.biorxiv.org/content/10.6...
Huge thanks to all co-authors and the #CarellaCapybaras for all the support ๐
