For September’s #JEMjc we would like to highlight the recent description of septal macrophages controlling adipocyte tissue plasticity www.science.org/doi/10.1126/...
It’s #JEM_Spotlight time again: this month we would like to highlight the detailed analysis of serological antibodies elicited after R21/Matrix-M malaria vaccine. Because, you know, vaccines work. doi.org/10.1084/jem.20241908
Following on from a great site visit at @cicbiogune.bsky.social last week, for #JEM_Spotlight I would like to highlight the work of @arkaitzcarracedo.bsky.social. A really interesting study investigating the role of LKB1 in metastatic prostate cancer. Take a look here 👉 doi.org/10.1084/jem....
Congratulations to Cedars-Sinai Postdoc Katarzyna Chojnacka, winner of the JEM Early Career Travel Award to attend the #Cytokines2025 meeting in Seattle. Learn more here: rupress.org/jem/pages/ea...
Tissue macrophages reside in anatomically distinct subtissular niches that shape their identity and function. In white adipose tissue (WAT), we identified three macrophage populations with distinct lo...
And if you needed any more convincing about the importance of #Tregs, check out this #Viewpoint written by Shimon for @jem.org's 125th anniversary about the role of Tregs in immunological self-tolerance and autoimmunity 👉 rupress.org/jem/article/...
Journal of Experimental Medicine
Montse Cols
Lucie Van Emmenis
Montse Cols
Shimon Sakaguchi recounts the work that lead to the identification of regulatory T cells.
rupress.org
Back to school, back-to-back #JEMLegacy with this study of neutralization tests for poliomyelitis in newborn infants and mothers…from 1930! tinyurl.com/59nnnuan
In light of Monday’s #Nobel Prize in Physiology or Medicine announcement, for #JEMLegacy let’s look back at one of Shimon Sakaguchi’s early @jem.org papers from 1985! rupress.org/jem/article/...
Happy New Year from all of us @jem.org. For this month’s #JEMLegacy we are going back to the 90s with this report on lymphotoxin’s role in chronic inflammation
tinyurl.com/2ua2cezw
Great message from Jim Allison on how we need to keep doing science. Even nicer shoutout to JEM on the interplay between CTLA-4 and ICOS enhancing ICI (tinyurl.com/4rebxhuj and tinyurl.com/42fnrbvb). Attending the Keystone Immunotherapy? Come and say hi 👋 #KSCancerImmune26
For this month #JEMjc we would like to highlight this study from Eva Harris lab linking anti-NS1 IgA antibodies in plasma from a primary ZIKV infection, to drive neutrophil activation and correlate with increased risk of subsequent severe DENV2 disease. More here:
www.nature.com/articles/s41...
Montse Cols
The study unveils that potent combination therapies remodel TAMs to antitumor proinflammatory M1-like macrophages crucial for their therapeutic efficacy. I
tinyurl.com
Neutralization tests for the virus of poliomyelitis on blood serum of urban mothers and their newborn infants showed that immunity was present in ten out o
This study reveals that anti-NS1 IgA antibodies in plasma, induced by prior Zika virus infection, activate neutrophils, underlying severe dengue disease upon a subsequent DENV2 infection, uncovering a...
