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tRNA m¹A modification regulates cholesterol biosynthesis to promote antitumor immunity of CD8⁺ T cells. From Shan Miao, Hao Li, Xiaohan Song, Youqiong Ye, Ru-Juan Liu, Hua-Bing Li and colleagues: rupress.org/jem/article/... 📘 Part of JEM #Cancer Collection: rupress.org/jem/collecti... #EACR2026
Ward, Kar, Balan, and Bhardwaj @bhardwajlab.bsky.social review how conventional type 1 #DendriticCells (cDC1s) coordinate antitumor immunity through cross-presentation, immune cell networking, and spatial organization in tumors. rupress.org/jem/article/... #CancerFocus #Immunotherapy
Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis. From Adrian Gervais, Aurélie Cobat, @casanovalab.bsky.social, Emmanuelle Jouanguy et al: rupress.org/jem/article/... 📘 From our Clinical #Immunology Collection 👉 rupress.org/jem/collecti... #FOCIS2026
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Publish your findings quicker through JEM manuscript transfers. “The handling of the transfer by the JEM editors and staff was excellent.” — Tim Willinger, JEM author rupress.org/jem/pages/tr...
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#Radiotherapy induces YTHDF2 in #DendriticCells impairing cross-presentation and T cell function, from Dapeng Chen, Chuan He, Hua Laura Liang, Ralph Weichselbaum and colleagues rupress.org/jem/article/... 📘 From our Clinical #Immunology Collection 👉 rupress.org/jem/collecti... #FOCIS2026
Read Sensing of metabolic signals via GPR183 promotes occupation of lung #macrophage niches by #monocytes rupress.org/jem/article/...
Attending #FOCIS2026 in San Francisco? Do not miss 📃 the Late Breaking Abstract session TODAY June 10, 4pm-6pm! The session will be chaired by our Executive Editor Natalie Cain (@nataliecain.bsky.social)! @focisimmunology.bsky.social
LCK’ed in: #InbornErrorsOfImmunity in LCK reveal how TCR signaling is calibrated. Review from Ahmet Eken, Sara A. Johnson, Serife Erdem, and Elena Wen-Yuan Hsieh: rupress.org/jem/article/... 📘 From our Clinical #Immunology Collection 👉 rupress.org/jem/collecti... #FOCIS2026
Harms Pritchard, @marionpepper.bsky.social et al. dissect key CD4⁺ T cell/B cell interactions to define signals that govern the development of memory B cell populations. rupress.org/jem/article/... #InfectiousDisease #HostDefense #LymphocyteBiology #BCells