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For this month #JEMjc we would like to highlight this study from Eva Harris lab linking anti-NS1 IgA antibodies in plasma from a primary ZIKV infection, to drive neutrophil activation and correlate with increased risk of subsequent severe DENV2 disease. More here: www.nature.com/articles/s41...
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This study reveals that anti-NS1 IgA antibodies in plasma, induced by prior Zika virus infection, activate neutrophils, underlying severe dengue disease upon a subsequent DENV2 infection, uncovering a...
IgA-driven neutrophil activation underlies severe dengue disease after primary Zika virus infection in humans - Nature Immunology
www.nature.com
Montse Cols