Once in a while, we get the privilege to enjoy works like this:
www.science.org/doi/10.1126/...
#InterferonPower! Thrilled for our latest work @cp-cell.bsky.social! With @danielboehmer.bsky.social, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IVđ) #interferons! Freeđ authors.elsevier.com/a/1leKGL7PXu...
Out today in Nature - our collaborative work with Ryan Flynn's lab, led by Dr. Peiyuan Chai with support from Dr. @sinakheiri.bsky.social and @shahjess.bsky.social from our group. Exciting findings showcasing how glycoRNAs can modulate angiogenesis!
Donât trust the expertsâ? Thatâs not democracy, thatâs recklessness.
On a plane, I want a pilot.
In a hospital, I want doctors and scientists who understand the evidence.
Expertise isnât religion or authoritarianism â itâs training, accountability, and data.
Ignore it and we all pay the price.
đšNew Paper in Cell đ§”đ
Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.
We were very excited (and lucky!) to contribute to this collab. effort.
đŠ âHuman monoclonal antibodies targeting A35 protect from death caused by mpoxâđŠ
doi.org/10.1016/j.cell.2025.08.004
I'm glad to see this being covered - because, frankly, this is a death-blow to collaborative science - however, the assumption of good faith in any of these decisions by reporters is mind-boggling.
This is happening for one reason - to assure top-down control of what gets funded and what does not.
Huge advance in glycoRNA biology. Congrats to @raflynn5.bsky.social and all of the wonderful authors! Canât wait to see what you guys do next!
In our latest episode, @woodrufflab.bsky.social and @kevinbonham.com talk about glycoRNAs, and the way they're shielded from the immune system in a new paper from the labs of @raflynn5.bsky.social and @vijayrathinam.bsky.social đ§Ș
audiommunity.org/episodes/epi...
Sugar coats shield immunogenic RNA modification:A new function for RNA glycosylation: Molecular Cell www.cell.com/molecular-ce... @raflynn5.bsky.social @vinnieviruses.bsky.social
Thanks to Autoimmunity podcast @kevinbonham.bsky.social & @woodrufflab.bsky.social for discussing our glycoRNA paper w/ @raflynn5.bsky.social @vinnieviruses.bsky.social
Defense-associated reverse transcriptases (DRTs) are widespread bacterial anti-phage systems that use unconventional mechanisms of polynucleotide synthesis. We show that DRT3, which comprises two dist...
A new function of glycosylated RNAs has been discovered by Graziano et al. in which
the glycosylation of RNA molecules shields acpÂłU RNA modification from triggering
innate immune responses.
In our latest episode, @woodrufflab.bsky.social and @kevinbonham.com talk about glycoRNAs, and the way they're shielded from the immune system in a new paper from the labs of @raflynn5.bsky.social and @vijayrathinam.bsky.social đ§Ș
audiommunity.org/episodes/epi...
RFK Jr: We need to stop trusting the experts... Trusting the experts is not a feature of science or democracy, it's a feature of religion and totalitarianism.
Science update from my postdoc Peiyuan Chai - his work âglycoRNA complexed with heparan sulfate regulates VEGF-A signalingâ is now published @nature.com uncovering a new layer or glycoRNA-regulation of growth factor mediated control physiological processes rdcu.be/e1bBX
Science update from my postdoc Peiyuan Chai - his work âglycoRNA complexed with heparan sulfate regulates VEGF-A signalingâ is now published @nature.com uncovering a new layer or glycoRNA-regulation of growth factor mediated control physiological processes rdcu.be/e1bBX
The US NIH is stepping back from 'top-down' science.
My latest analysis for @nature.com shows that funding calls have plummeted by 90%, funneling billions into broad, 'investigator-initiated' ideas, rather than targeted, agency-driven ones.
A massive shift for the American biomedical enterprise.
