Our lab in Czechia investigates cellular signaling during developmental and homeostasis processes using a Xenopus embryo 🐸 and tissue cells 🧫.
See more at👇
https://www.sci.muni.cz/ofiz/en/harnos-lab-2/
Alumni @CDRBSinai (🇺🇸), @uniwuerzburg (🇩🇪)
Jakub Harnos lab
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So proud of my team.
Talented, hardworking, growing every day.
Being there for them is my biggest joy.
Harnos Lab 2026 🐸 😍 🥳
A new Master is born 🎓
Kristýna finished her Master’s degree in the Harnoš lab 🔬
Our fourth Master - congratulations 🚀
Welcome to Brno 🇨🇿
Our two new exchange students, Alba Macipe Feito and Ana Moreno Llorente 🇪🇸
They will study molecular and cell signalling for the following four months 🔬
Good luck and godspeed 🚀
🐸 Amphibians take over Europe!!
📍 Prague. July 3–5, 2026.
The European Amphibian Conference 2026 is coming: 3 days of cutting-edge science, bold ideas, iconic speakers, and serious frog & axolotl energy ✨
👉 Register. Submit. Be there. Do not miss it.
amphib-conf2026.sciencesconf.org?lang=en
Why do we lose so much talent in academia?
Let’s talk about it – openly, together, responsibly.
NEXT TUESDAY AT 5:30 PM.
PI Forum Brno #7 | Feb 3 @ CEITEC MU
For all PIs, PhDs & researchers in Brno.
Chaired by @fabianlab.bsky.social
When you urgently need the restroom but get lost in a Xenopus development poster instead… 🐸🧠
Thanks to my lab heroes Lorena & Douglas for representing the #DaysOfOpenDoors at Masaryk University
#frogpower #MUNI
New Paper Alert!
1982: WNT discovered
1990s: NOTCH enters the stage
2000s: “Let’s study pathways separately.”
2025: “Actually, they talk to each other.”
Welcome to the era of WNT-NOTCH crosstalk
Great collaboration with Mašek lab (CZ) and G. Collu (US)
royalsocietypublishing.org/rsob/article...
🧪🐸 PhD position open in the Harnos Lab (Masaryk University, Brno)!
We study cell migration, WNT/PCP signaling, mitochondria & energy in Xenopus.
Start: June 2026 (flexible)
Apply by Feb 28, 2026
📩 [email protected]
#PhDposition #CellBiology #Mitochondria #Xenopus #WNT #PCP
Just published a #BehindThePaper blog post about our new paper on PRICKLE3 and WNT/PCP signalling! 🧬 Check out the story behind the science and what we learned along the way 👇
communities.springernature.com/posts/behind...
Together with @harnoslab.bsky.social, we compiled what is known about direct interactions of Wnt and Notch components, and advanced the testable framework of how the crosstalk could allow for a more polarized cellular response to one pathway or the other.
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Jakub Harnos lab
Abstract. Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordinatio
Behind every research paper, there is a long story that is usually invisible to the reader. Our paper is no exception. What began as a focused cell biology project gradually developed into a broad, co...
🔥 New paper out!
PRICKLE3 is not just another PRICKLE.
It stabilizes VANGL, blocks CK1ε phosphorylation, suppresses RNF43, and rewires WNT/PCP signaling across species.
Big mechanism. Big fun. 🐸🔥
www.nature.com/articles/s42...
Jakub Harnos lab
We mapped PRICKLE1–3 interactomes and identified PRICKLE3 as a key WNT/PCP regulator that stabilizes VANGL via CK1ε–RNF43 control, revealing a PRICKLE3-specific mechanism shaping polarity across verte...
