junior group leader at University of Würzburg || RNA biologist with a 🖤 for splicing || science & 🎨, #firstgen www.beuschlab.org
Irene Beusch
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19F NMR is such a powerful tool! Lovely NMR work ❤️
Irene Beusch
One week left to apply. Help us find new antimicrobials and understand the inner workings of bacteria – as a technical assistant in the Machine Biophotonics and Nanoscale Bacteriology labs at the Rudolf-Virchow-Zentrum, University of Würzburg – See details below (in German). Please spread the word.
❗️5 days left to apply for a PhD position in our group👇
Our genes come in bits & pieces!🧬Learn how splicing "cuts & pastes" RNA to create different proteins from a single gene, for its discovery the 1993 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=-x7H...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
Yale MB&B's Karla Neugebauer and Guillermina Kubaczka have been featured in a new @natmethods.nature.com piece 🌍🔬
The article spotlights researchers bridging the molecular and planetary scales to address global health challenges.
@karlaneugebauer.bsky.social
www.nature.com/articles/s41...
It‘s not always the best solution to do your CRISPR(i) screen at a low MOI (or the dogmatic 0.3-0.5 range 😉) - superinfection can give you a higher quality output!
Super cool to finally see some of @chnebster.bsky.social postdoc work out and published!
looking forward to reading this! Love to see an RRM-by-RRM dissection as similar principles are employed by so many multi-RBD proteins.
Very neat and cool!
Aktuelle Stellenanzeigen des Rudolf-Virchow-Zentrums / Current positions of the Rudolf Virchow Center
A nascent group of researchers sees planetary health as an urgent reason to bridge the molecular and planetary scales. This is shaping their strategies, methods, collaborations and outlook about their...
Passionate about transcription?
🚀 We’re recruiting a PhD student in Transcriptional Regulation at @ucph.bsky.social Start Summer 2026
Work with RNA, CRISPR, sequencing & proteomics in the Gregersen Lab @cgen2025.bsky.social
Meet us: gregersenlab.com
Apply by Apr 10, 2026👇
tinyurl.com/PhD-CGEN
How can a splicing factor bind to thousands of exons but regulate only a few of them? In our new preprint, we show that SRSF6 resolves this paradox through two distinct binding modes. @lab-nmr.bsky.social & @julianvonehr.bsky.social. Check it out:
www.researchsquare.com/article/rs-9...
What should Europe do when demand for #ERC funding keeps rising?
Restrict access or invest in excellence?
Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness
Consider to share & sign - see below 🧪
What should Europe do when demand for its most successful frontier research programme keeps rising?
Restrict access, or invest in the excellence it has created?
A new open letter, spearheaded by Sara...
Our new paper is out! Using 19F NMR, we show that Hfq rewires the conformational dynamics of a model sRNA in a site-specific manner. Uridines at the rim undergo faster exchange (~100 μs) than those in the proximal pore (~300 μs). Congrats Elise! 🎉🎉 www.sciencedirect.com/science/arti...
Michaela Müller-McNicoll
Nuclear magnetic resonance (NMR) spectroscopy is uniquely suited to probing motions on the microsecond to millisecond timescales that underlie RNA rec…
NAR breakthrough alert 🎉 Joint work with @mfeldbruegge.bsky.social on Rrm4. We dissect its modular RRM binding code & how domain combinations shape RNA interactions. Like finding needles in a haystack, comparative iCLIP sorts functional vs accessory sites. Work by Nina & @srimeenakshi.bsky.social
Woodson Lab
Zarnack Group
Lots of papers out today!
From Doug Black and Hong Zhou's labs: structural mechanism of RBM5 regulated splicing via U2 interactions
The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing
Shiheng Liu et al..
www.biorxiv.org/content/10.6...
A project from my postdoc in the McManus lab @mcmanuslab.bsky.social at UCSF @ucsfdc.bsky.social is out today 🎉
For years, pooled CRISPR screens have operated under a central assumption: one perturbation per cell.
We challenged that assumption. 🤯
www.nature.com/articles/s41592-026-03095-w
Stefan Oberlin
Aaron and the Hoskins Lab at UW Madison
www.biorxiv.org
This paper shows that high MOI sgRNA multiplexing maintains CRISPRi screen performance while enabling reduced cell numbers, challenging conventional reliance on low-MOI infections.
Breakthrough article 😊
Joint effort of teams Zarnack & König & Feldbrügge clarifies how multiple RNA-binding domains cooperate to identify functional important binding sites in vivo
doi.org/10.1093/nar/...
@zarnack-group.bsky.social
@könig-lab.bsky.social
@mibinet.bsky.social
#EMBOrnaLocalization
doi.org
Abstract. RNA-binding proteins (RBPs) utilize multiple RNA-binding domains (RBDs) to engage with extensive messenger RNA (mRNA) networks. Understanding the
