Swiss National Center of Competence in Research (NCCR): The role of RNA in disease mechanisms. Propelling research forward since 2014.
@snsf-ch.bsky.social @unibern.bsky.social @ethzurich.bsky.social
https://nccr-rna-and-disease.ch/
NCCR RNA & Disease
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A tiny chemical tweak changed medicine! 💉 Discover how RNA modifications made efficient mRNA vaccines against Covid-19 possible, for which the 2023 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=1SQd...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
Preprint by the Leidel, Thiel & Pillai labs with co-1st authors R. Pandey & N. Ebert "Loss of host factor-mediated m6Am methylation of the viral RNA cap impairs SARS CoV-2 replication" @biorxivpreprint.bsky.social
doi.org/10.64898/202...
@profvolkerthiel.bsky.social
@mcm5s2u.bsky.social
@unibe.ch
Why do we age? 🧬 Meet telomerase, the molecular machine that rebuilds chromosome ends and its roles in health & disease. For its discovery, the 2009 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=dXLE...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
Reprogramming cells with precision! 🎯 Learn how RNA interference (RNAi) silences specific genes to treat diseases. For its discovery, the 2006 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=rZY1...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
Our genes come in bits & pieces!🧬Learn how splicing "cuts & pastes" RNA to create different proteins from a single gene, for its discovery the 1993 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=-x7H...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
Imagine curing diseases by rewriting the code of life!🧬Discover how CRISPR/Cas9, guided by RNA, acts as molecular scissors to precisely edit genomes, for which the 2020 Nobel Prize in Chemistry was awarded
www.youtube.com/watch?v=0rz-...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org
NCCR RNA & Disease
Video
How did life begin?🧬Before DNA & proteins, RNA paved the way for modern life. Learn about "ribozymes". The discoverers of catalytic RNAs were awarded the 1989 Nobel Prize in Chemistry!
Watch the video with subtitles in DE, EN & FR:
www.youtube.com/watch?v=LjtN...
@snsf.ch @unibe.ch @ethz.ch
DNA holds the blueprints, but how are proteins built?Meet the ribosome, a nanomachine.For the studies of it,the 2009 Chemistry Nobel Prize was awarded.
Watch the video on YouTube with subtitles in English, French & German:
www.youtube.com/watch?v=2txJ...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org
Preprint by the Polacek lab and collaborators with first author EunBin Kong "Stress-induced vtRNA1-1 modulates redox homeostasis and ferroptosis susceptibility in hepatocellular carcinoma cells" @biorxivpreprint.bsky.social
doi.org/10.64898/202...
@unibe.ch
For gene expression,there exist "dimmer switches"!Discover how microRNAs fine-tune protein production in health&disease.For their discovery,the 2024 Nobel Prize in Physiology or Medicine was awarded.
www.youtube.com/watch?v=qoUo...
@snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social
