Are you getting enough vitamin B7? A recent #InnovativeTsinghua study by Assoc. Prof. Ai Zhao’s team, featured in @ebiomedicine.bsky.social, shows that adequate dietary biotin intake is linked to a lower risk of all-cause #dementia and #Alzheimer’s disease.
For more: bit.ly/4lDMpge
📣 Excited to share our recent paper that investigates how different SSRIs have an impact on the metabolism of neural cells 🧠
Please read our popular science summary at @ki.se web: news.ki.se/new-study-sh...
🧪 The publication is open access at @ebiomedicine.bsky.social, DOI: doi.org/10.1016/j.eb...
Ye et al. recorded from four thalamic nuclei in 64 patients with #DrugResistantEpilepsy. Spike-fast activity—not spike rate—predicted poor outcomes. The study also maps physiological thalamic SEEG patterns routinely misread as pathology.
Also in this issue: Kagiava & Chen et al. review #IntrathecalGeneTherapy for neurological disorders. The case for intrathecal over IV delivery is now clinically supported across SMA, giant axonal neuropathy, CLN7, and ALS.
Tsinghua University
A big congrats to Stefano, Elena, and team for this publication! 🥳 New work demonstrates the relevance of T cell PKM2 in MS in humans (where before the role had been shown in mice) bringing potential novel therapies in MS/autoimmunity! #immunometabolism #tcells #ms
www.thelancet.com/journals/ebi...
Only ~1 in 500 seizure-focus spikes propagate to the thalamus during sleep—yet thalamic activity still predicts surgical failure in #FocalEpilepsy. New research in eBioMedicine helps explain why.
Happy to share our new publication on the role of endothelial cells in age-related cognitive dysfunction, published in
@ebiomedicine.bsky.social. Thanks to all coauthors, incl. Dimitrios Spyropoulos, @dorotheazi.bsky.social, @talongden.bsky.social, and many more. www.thelancet.com/journals/ebi...
This month's editorial takes stock of #organoids: what the field has delivered, where evidence hasn't kept pace with ambition, and what translation will actually require.
Full issue at thelancet.com/ebiom
Abishek Arora, PhD
A new study from Karolinska Institutet shows that different SSRI medications affect metabolic processes in developing nerve cells in distinct ways. Alterations in energy metabolism, oxidative stress a...
New paper out in The Lancet @ebiomedicine.bsky.social on the oral–brain axis 🦷🧠.
Does the bacterial community living in our gum pockets relate to brain health? In 1,026 people from the population-based PAROMIND cohort, we show the answer is yes. 🧵
#neuroskyence #microbiome #dementia
Excited to share this labor of love on the dynamics of CD4 T cells in HIV infection—now published in @ebiomedicine.bsky.social !
www.thelancet.com/journals/ebi...