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A big congrats to Stefano, Elena, and team for this publication! 🥳 New work demonstrates the relevance of T cell PKM2 in MS in humans (where before the role had been shown in mice) bringing potential novel therapies in MS/autoimmunity! #immunometabolism #tcells #ms www.thelancet.com/journals/ebi...
Our data suggest that PKM2 may represent a therapeutic target to limit T cell-driven inflammation in MS and potentially other human autoimmune diseases.
www.thelancet.com
Targeting pyruvate kinase M2 (PKM2) reduces T cell pathogenicity in multiple sclerosis
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Marah C Runtsch