The third round is now open!
I will be hosting a webinar with my colleagues on Monday 27 April at 1pm. To sign up please go to: shorturl.at/Vuwib
International applicants are eligible to apply!
Nicholas Farmer
The LMB Rising Talent Fellowship is open for new applicants!
Aimed at Black heritage scientists, the Fellowship offers a 3-year postdoctoral position beginning Oct-Dec 2026.
Visit our website for more info: mrclmb.ac.uk/careers-and-...
Please circulate this post to anyone who might be interested!
Meet our new ECR Representatives for the Proteostasis UK ECR Network!
This team will be delivering a range of resources, events, and initiatives to support the career development of ECRs
Sign up to the network to access exclusive opportunities for ECRs 👉 Join here: proteostasisuk.co.uk
Very cool probe to label doublet MTs and therefore centrioles across different species and set ups (from live imaging, STED and expansion)!😍
www.nature.com/articles/s41...
cryoCLEM of dopaminergic neurons from @lycasworks.bsky.social and Simon Erlendsson: doi.org/10.1083/jcb....
MRC Laboratory of Molecular Biology
Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4).
www.nature.com/articles/s41...
Happy to share my first adventure in #TeamTomo in collaboration with the talented @inaharasimov.bsky.social. It was a fun experience experience with a lot of learning along the way.
CenSpark is a dual-ligand fluorescent probe binding simultaneously inner and outer microtubule sites, a configuration unique to doublet and triplet microtubules, enabling selective live imaging of cen...
Lycas et al. develop a cryo-CLEM workflow to characterize the ultrastructure of dopaminergic varicosities. They resolve in situ structures of TRiC/CCT and
Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional ...
New preprint! We asked a simple question:
How do very different activating adaptors all activate dynein?
Turns out: same architecture, wildly different implementations 🧵👇
doi.org/10.64898/202...
ProteostasisUK
New preprint from the lab, looking at how multiple different adaptors interact with dynein! Work led by @amicoennio.bsky.social.
Available now on BioRxiv: doi.org/10.64898/202...
doi.org
Our story on RNA recognition by Egl-BicD is now published!
Also delighted to share the accompanying News & Views article by Florence Besse and Andres Ramos, which beautifully highlights the work.
Paper: www.nature.com/articles/s41...
News & Views: www.nature.com/articles/s41...
The hidden rules behind mRNA transport.
A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs.
Read more: mrclmb.ac.uk/news-events/...
#LMBNews @cellbiol-mrclmb.bsky.social 🧪
doi.org
Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional ...
New preprint! We asked a simple question:
How do very different activating adaptors all activate dynein?
Turns out: same architecture, wildly different implementations 🧵👇
doi.org/10.64898/202...
The hidden rules behind mRNA transport.
A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs.
Read more: mrclmb.ac.uk/news-events/...
#LMBNews @cellbiol-mrclmb.bsky.social 🧪
Ennio
doi.org
Ennio
MRC Laboratory of Molecular Biology
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
Video
Carter Lab
Carter Lab
Carter Lab
Tet Trim-Away: A conditional rapid protein degradation system for Tetrahymena thermophila https://www.biorxiv.org/content/10.64898/2026.05.29.728803v1
