Such a fantastic week at #KSBeyondAntibiotics26! Amazing science, timely conversations about AMR & bacterial infections, and AWESOME people. Thanks to my co-organizers and everyone who joined us in beautiful Breckenridge!
@dariavantyne.bsky.social @maribyndloss.bsky.social @kimingeneva.bsky.social
👍
A nice story by Ami Bhatt's lab.
A transposable element insertion upstream of a folate transporter formed a strong promoter, increasing transcription and improving relative fitness under folate limitation.
We have recently reported that folate biosynthesis
www.nature.com/articles/s41...
Here is it! Super new science from us on horizontal gene transfer & bact defense systems! Liyana OW YONG discovered the first-of-its-kind defense factor AbjA that triggers 'abortive conjugation' as a defense mechanism, by targeting the T4SS! How neat?! #MicroSky 1/7
www.biorxiv.org/content/10.6...
Vancomycin tolerance and dispersion of dual species biofilms of Clostridioides difficile and Vancomycin-resistant Enterococcus faecium https://www.biorxiv.org/content/10.64898/2026.03.09.710618v1
Study 2: Culture-enriched metagenomic sequencing reveals within-patient diversity and transmission of vancomycin-resistant Enterococcus faecium
www.medrxiv.org/content/10.6...
Important study by Chris Connor and Ben Howden (both not on here?) @unimelb.edu.au
'Global dissemination of optrA-mediated linezolid resistance in enterococci', major roles of mobile genetic elements in the dissemination of this important resistance determinant
academic.oup.com/jac/article/...
Frederick's @frederickreinhart.bsky.social paper on E. faecalis egress from host cells following intracellular replication is now up at #PLOS Pathogens. 😎 Check it out! dx.plos.org/10.1371/jour...
Adaptation of Enterococcus faecalis to intestinal mucus revealed by a human colonic organoid model
#mSystems from Alexandre Persat
with @kimingeneva.bsky.social
journals.asm.org/doi/10.1128/...