Frederick's @frederickreinhart.bsky.social paper on E. faecalis egress from host cells following intracellular replication is now up at #PLOS Pathogens. 😎 Check it out! dx.plos.org/10.1371/jour...
Author summary Pathogenic bacteria are traditionally classified as either “intracellular” or “extracellular”, but growing evidence suggests that many extracellular bacteria also adopt transient intrac...
There's more! @frederickreinhart.bsky.social now shows Fsr quorum sensing turns on during intracellular replication, driving GelE-dependent host cell lysis/egress, a model for how intracellular “factories” become new extracellular inocula, primed for reinfection. 5/n www.biorxiv.org/content/10.6...
Kimberly Kline 🏔
Enterococcus faecalis is a common opportunistic pathogen, frequently isolated from chronic wounds, yet the mechanisms underlying its virulence and persistence in this niche remain incompletely underst...