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Mostly about bacterial gene/protein regulation & function, esp. with Borrelia burgdorferi and Lyme disease. Professor at U Kentucky, views are my own. He/him Lab= http://microscopist.net/Stevenson_Lab.html UK= https://medicine.uky.edu/users/bstev0
Brian Stevenson Ph.D. spirochete lab









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Deletion of badR and replacement of eight conserved residues with alanines in CsrA of resulted in Borrelia burgdorferi mutants with upregulation of RpoS and several immunogenic lipoproteins, that were incapable of colonization in mice. journals.asm.org/doi/10.1128/... #MicroSky
Wash cycle complete! At the Institute for Cancer Research / Royal Marsden Hospital with @generoom.bsky.social
When Clades Collide: Genomic Admixture in Blacklegged Ticks (Ixodes scapularis) from the Great Plains "~50% infection rate (of B. burgdorferi) in ticks from Iowa and northeastern Nebraska, whereas ticks from Kansas show no evidence of B. burgdorferi infection" www.biorxiv.org/content/10.6...
Met up with old friends from Yale postdoc days during our recent holiday in England. Included an exciting tour of the genomics facilities at Royal Marsden Hospital / Institute for Cancer Research, where Mike is Scientific Director & Professor. ‪@generoom.bsky.social‬
Just announced! This year’s Tick Borne Disease Research Program of CDMRP. cdmrp.health.mil/funding/tbdrp #MicroSky
“New Concepts in Prokaryotic Virus-Host Interactions” 🗓️ 5–7 October 2026 📍 Harnack House, Berlin, Germany #MicroSky
NIH awards the University of Kentucky $11.3 million for COBRE Phase 2 pharmaceutical research Pleased to be a part of this continuing research program uknow.uky.edu/research/nih...
The wild, wild west of plasmids: First insights into comparative genomics of Borrelia burgdorferi sensu lato journals.plos.org/plosone/arti... pubmed.ncbi.nlm.nih.gov/42102105/ #MicroSky
On Borrelia burgdorferi lipids: A lipid compendium of a metabolically compromised bacterium provides insights into lipid acquisition, biosynthesis, and metabolism www.biorxiv.org/content/10.6... #MicroSky
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility onlinelibrary.wiley.com/doi/full/10.... #MicroSky
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Protective efficacy of mutant strains of Borrelia burgdorferi as potential reservoir host-targeted biologics against Lyme disease | Infection and Immunity
Lyme disease is the most common vector-borne disease in the United States with 89,000 cases reported to the Centers for Disease Control and Prevention (CDC, Atlanta) in 2023. It is estimated that arou...
journals.asm.org
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
The University of Kentucky has been awarded a prestigious $11.3 million Phase 2 Centers of Biomedical Research Excellence (COBRE) grant from the National Institute of General Medical Sciences of the N...
uknow.uky.edu
NIH awards UK $11.3 million for COBRE Phase 2 pharmaceutical research
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Brian Stevenson Ph.D. spirochete lab
Funding Opportunities-FY26 TBDRP, Congressionally Directed Medical Research Programs (CDMRP)
TBDRP funding opportunities currently available
cdmrp.health.mil
Brian Stevenson Ph.D. spirochete lab
Finally caught up with Borrelia guru, friend and former partner in crime on the rubgy pitch, @bstevensonlab.bsky.social after a (very) long time. Beers were had 🍺 We need to get a bigger labcoat for next time. 😃
📢 Registration for our International Symposium on “New Concepts in Prokaryotic Virus-Host Interactions” is now open! 🗓️ 5–7 October 2026 📍 Harnack House, Berlin, Germany ➡️ Information and registration: spp2330.de/symposium-20...
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New Concepts in Prokaryotic Virus-Host Interaction
Mike Hubank