Deletion of badR and replacement of eight conserved residues with alanines in CsrA of resulted in Borrelia burgdorferi mutants with upregulation of RpoS and several immunogenic lipoproteins, that were incapable of colonization in mice.
journals.asm.org/doi/10.1128/...
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Lyme disease is the most common vector-borne disease in the United States with 89,000
cases reported to the Centers for Disease Control and Prevention (CDC, Atlanta) in
2023. It is estimated that arou...
