Cell Bio@Harvard Med- dedicated to unraveling how the machines of the cell work. Specializing in membrane/organelles, ubiquitin & protein quality control, chromatin regulation, proteomics, metabolism, and sensory perception.https://cellbio.hms.harvard.edu/
Harvard Med Cell Biology
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Collaboration between Schulman lab @mpi-biochem, @harperlabhms.bsky.social & Hanna Lab @BWH/HMS reveals structural basis for Parkinson's risk genes FBXO7 & PI31/PSMF1 interaction with each other & with the proteasome core particle. @asapresearch.parkinsonsroadmap.org www.biorxiv.org/content/10.6...
Cancer, communication and connecting continents - insights from our own David Pellman upon election to EMBO. www.embo.org/people/cance...
Historically, viruses were thought to primarily use host cell's translational machinery. New work from @harvardcellbio.bsky.social faculty Amy Lee reveals that a giant DNA virus encodes its own IF4F initiation complex, suggesting an unexpected evolutionary innovation. www.biorxiv.org/content/10.1...
CONGRATULATIONS!! to our own Steve Liberles for his election to the National Academy of Sciences for his work on vagus nerve sensory perception and gut-brain communication. @hhmi-science.bsky.social www.nasonline.org/news/2026-na...
New work from our own Liberles Lab (liberles.hms.harvard.edu) demonstrates that vagal mechanoreceptors monitor the cardiac cycle and initiate a blood-volume-dependent reflex that defends the constancy of circulation www.nature.com/articles/s41...
New work from @harvardcellbio.bsky.social faculty Amy Lee uncovered fundamental aspects of protein translation initiation by a giant DNA virus. www.sciencedirect.com/science/arti...
New work from the Moazed lab reveals the requirements for establishment & epigenetic stability of mammalian heterochromatin! www.cell.com/molecular-ce...
CONGRATULATIONS! to our own Lucas Farnung on being recognized by a Mark Foundation for Cancer Research Emerging Leader Award. Well deserved! themarkfoundation.org/2026/01/2026...
Single molecule studies from Arda Mizrak in the Farese/Walther @msk & Harper Labs @harvardcellbio.bsky.social shows how lipid droplet proteins track through ER networks to ultimately partition into nanodomains on droplets, dependent upon Trp-containing hairpin motifs www.nature.com/articles/s41...
Exciting work from @lucas.farnunglab.com & @voslab.org report structures of CTCF-nucleosome complexes, revealing that CTCF dimers promote oligomerization of nucleosomes into defined higher-order assemblies involving specific histone-histone and CTCF-CTCF interactions. www.biorxiv.org/content/10.6...
Harvard Med Cell Biology
Harvard Med Cell Biology
Mizrak et al. use single-molecule tracking to dissect mechanisms of protein targeting to lipid droplets. They show that nanodomain-based confinement drives selective protein accumulation on lipid drop...
WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original res...
A vagal reflex to blood volume changes in the heart involves PIEZO2 and helps to stabilize blood pressure in an upright posture and after blood loss.
Tatarakis et al. study how H3K9me3 heterochromatin is formed and inherited in mammalian
cells. Using a synthetic heterochromatin assembly system and genetic screens, they
uncover requirements for init...
In contrast to living organisms, viruses were long thought to lack protein synthesis machinery and instead depend on host factors to translate viral t…
In contrast to living organisms, viruses were long thought to lack protein synthesis machinery and instead depend on host factors to translate viral transcripts. Here, we discover that giant DNA virus...
www.biorxiv.org
The Mark Foundation for Cancer Research is proud to announce the recipients of the 2026 Emerging Leader Awards (ELA), recognizing five visionary early-career scientists poised to make significant impa...
