Single molecule studies from Arda Mizrak in the Farese/Walther @msk & Harper Labs @harvardcellbio.bsky.social shows how lipid droplet proteins track through ER networks to ultimately partition into nanodomains on droplets, dependent upon Trp-containing hairpin motifs www.nature.com/articles/s41...
www.nature.com
Mizrak et al. use single-molecule tracking to dissect mechanisms of protein targeting to lipid droplets. They show that nanodomain-based confinement drives selective protein accumulation on lipid drop...
