So happy to see that Nature Cancer had chosen our picture as the cover of their September issue together with the publication of our paper on stem cell plasticity during prostate tumor initiation. Congratulations to @ChenJiang919 and @yura__song
Come join us and @svanharanta.bsky.social @cedric-blanpain.bsky.social Roger Gomis @irbbarcelona.bsky.social @obenaufa.bsky.social Karin de Visser @nkinl.bsky.social @grauperalab.bsky.social @prat-aleix-md.bsky.social @vickysanzmoreno.bsky.social @johannajoyce.bsky.social @momobentires.bsky.social
Out @nature.com: Clonal tracing with somatic epimutations
🧬 Single cell methylome encodes cell state & clonal identity
🔨 EPI-Clone reads out both (+mutations, +RNA) at scale
🩸 Clonal expansions of HSCs are universal from age 50, not driven by CH mutations
doi.org/10.1038/s415...
🧵
Leaving our #EACR congress in Lisbon appreciating both the incredible science and the amazing community we have - with many wonderful friends!
#EACR2025 🤩
@helloeacr.bsky.social
@adaptmet.bsky.social
@msmelanoma.bsky.social
@arkaitzcarracedo.bsky.social
@svanharanta.bsky.social
Thanks a lot to Alejandro Sifrim (KUL) that co-supervised this work with me, Sandrine Rorive (Curepath), who performed the pathology examination and all our other collaborators.
I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprograming of prostate tumor initiating cells published in
@NatureCancer
. Congrats
@ChenJiang919
and
@yura__song
, the first authors,
www.nature.com/articles/s43...