What can you do to improve your microscopy images?
I often receive questions regarding how to take better images, so let’s start with the basics: improve your sample preparation! No microscope can make a miracle if your samples don’t look great! Things I don’t do anymore: (1/5)
Studying the proteome of amyloid-beta plaques in Alzheimer's disease without the need to perform immunohistochemical staining? Sounds like science-fiction but now possible thanks to this great collaborative project!!
@baaylab.bsky.social @axlmsg.bsky.social #proteomics #alzheimers 1/3
At #ADPD2025?? Go check today&tomorrow Sarah Basile at poster 174 on #amyloid-beta nitration and its role in fibrillation and #neuroinflammation in #Alzheimer. We would LOVE to hear your thoughts!
Interested to see how advanced microscopy holds the power to transform our understanding of therapeutics🔬🧠…come see our latest work. #AAIC25
Hall G session 2-3.30 pm integrative neuropathology in ADRD at 2.20 pm sharp
@drneurochic.bsky.social
By going beyond ‘Atypical’ / ‘AD’ @jeffandthebrain.bsky.social got me excited about interesting unexplored avenues. And! A whole lot of relevant papers I still need to read. Check the recording @istaart.bsky.social available in ~3 weeks if you missed it!
Danielle Beckman
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social
authors.elsevier.com/a/1lxn85FFzL...
🎉 @istaart.bsky.social #AtypicalAD PIA Executive Committee is elected!
Chair: Keir Yong
Vice Chair: @baaylab.bsky.social
Programs Chair: Rosaleena Mohanty
Communications Chair: Colin Groot
Early Career Representative: @sararosedunlop.bsky.social
Immediate Past Chair: @rikossenkoppele.bsky.social
📢 Excited to announce the lineup for the @istaart.bsky.social #AtypicalPIA FRS at #AAIC25 on July 29! Mark your calendar to join us in person or online with @neusfalgas.bsky.social @leatgrinberg.bsky.social @rikossenkoppele.bsky.social @baaylab.bsky.social Drs. Deepti Putcha, Keir Yong, Colin Groot!
Kicking off #CONY2025 in style w/ debate: "Should atypical #Alzheimer be included in trials?" What do you think? discussion w/ @rosaleenam.bsky.social @keiryong @rikossenkoppele.bsky.social & Judith Aharon & support @alzassociation.bsky.social @istaart.bsky.social
Baayla Boon
Baayla Boon
Baayla Boon
Baayla Boon
Lea T. Grinberg
Excited to share our findings on how APOE genotype impacts cell responses to AD using human brain snRNAseq. Huge thanks to the team for all the hard work! @drneurochic.bsky.social @mayoclinic.org @cp-neuron.bsky.social
