Incoming SNSF Ambizione Fellow (2026-2030) at D-USYS, ETH Zürich. Interested in epigenomes, natural variation and polyploidy evolution in plants.
Currently postdoc at ETH (Bomblies lab). PhD from Max Planck Institute for Biology Tübingen (Weigel lab).
Thanvi Srikant
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📣Our paper is out! 🤩 We found that local modification of H3K9me3 using CRISPR/dCas9 at hotspots changes crossover activity, bringing us closer to targeted recombination in plants.🌱
Huge thanks to @szymanskalejman.bsky.social, Wojtek, Ania, and Karolina!
www.science.org/doi/10.1126/...
I am happy to announce the launch of a new Arabidopsis genomics resource! Check out arabidopsislyrata.org Now you can easily look at the natural genetic variation across the entire species range of A. lyrata and A. arenosa.
Resequencing hundreds or thousands of individuals from the same species has become routine... but processing all those genomes efficiently? Still a headache!
Here's my solution that used to be lab-internal but that I am happy to share:
crolllab.github.io/genomepanel_...
We identified an initial set of 30+ toolkit genes from literature, but encourage the community to test & expand our model! Further questions incl. (1) how similar/diverse toolkits function across environments (2) how toolkit proteins affect (epi)genomic features in various cells/tissues/individuals
Studying the epigenetic toolkit (and allelic variation in toolkit genes) as an evolvable trait could help predict how different plant species and populations maintain homeostasis – both under short-term stress/nutrient fluctuations and long-term environmental shifts.
Can we tune a plant’s epigenetic toolkit to disrupt plant homeostasis in ways that enable phenotypic innovation?
🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!
www.sciencedirect.com/science/arti...
✨Call open for a fully-funded PhD position✨
Looking for an enthusiastic student to join my upcoming Ambizione research group (🌱 Epigenome Diversity Lab 🌱, www.epidiversitylab.org) at ETH Zürich, starting August 2026! Apply here ↘️
jobs.ethz.ch/job/view/JOP...
Application deadline: January 31st, 2026
How can plants maintain their genomic identity while also responding to the environment? @hajkdrost.bsky.social and I propose an "epigenetic toolkit" – a suite of epigenetic regulators that mediate the physiology-epigenome-genome crosstalk for adaptation. Read more here:
www.cell.com/trends/plant...
It was a pleasure collaborating with @hajkdrost.bsky.social again, building on ideas that originated from our previous review on stress-induced epigenetic variation : www.frontiersin.org/journals/pla...
