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📣Our paper is out! 🤩 We found that local modification of H3K9me3 using CRISPR/dCas9 at hotspots changes crossover activity, bringing us closer to targeted recombination in plants.🌱 Huge thanks to @szymanskalejman.bsky.social, Wojtek, Ania, and Karolina! www.science.org/doi/10.1126/...
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Targeting chromatin modifiers to DNA hotspots reveals causal link between histone marks, transcription, and meiotic recombination.
www.science.org
Modifying meiotic recombination by targeting chromatin regulators to crossover hotspots in Arabidopsis
Piotr Ziolkowski