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The LEO Foundation Skin Immunology Research Center (SIC) paves the way to a better understanding and treatment of the skin diseases that plague a quarter of the world's population.
LEO Foundation Skin Immunology Research Center (SIC)









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3 great days at the SIC Summer School in Hornbæk with inspiring talks, short talks from young researchers, poster sessions, networking, and a trip to Esrum Abbey. Thank you to all speakers, participants, organisers, and the LEO Foundation for supporting the summer school. See you 24–26 May 2027.
Elimination of cancer T cells with little collateral damage to healthy T cells by TCRVβ-ADC Congratulations to Chella K Vadivel at the LEO Foundation Skin Immunology Research Center (SIC) and co-authors with this new treatment strategy published in Blood Adv 👌👏💪🎊🎉🎼 lnkd.in/e4mWCpUT
I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology. #TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance @sic-ucph.bsky.social @ludwigcancer.bsky.social doi.org/10.1126/scii...
SIC researchers have delved deeply into fibroblasts of the intestines. They describe how these cells organise our immune responses in structures called ‘gut associated lymphoid tissues’. @ursmoerbe.bsky.social sic.ku.dk/news/2026/fi...
Researchers at SIC recently characterised the diversity of phagocytes in the intestine of healthy people and in those with inflammatory bowel disease. They describe precursor phagocyte populations and the emergence of activated dendritic cells in IBD. sic.ku.dk/news/2026/di...
This work was spearheaded by Maria Gluud and the team at Skin Inflammation & Cancer @niels-odum.bsky.social at @sic-ucph.bsky.social and our fantastic collaborators! Finally, this study would not have been possible without the support from LEO Foundation, DFF, @cancer.dk @novo-nordisk.bsky.social
SIC’s annual activity report for 2025 is now available online. Read latest updates from the Center here: sic.ku.dk/news/2026/an...
Researchers at SIC have analysed the skin’s response to exposure to the contact allergen, nickel. They found that the response became more severe with repeated exposures and was likely due to a strong skin-resident T cell response to nickel. academic.oup.com/bjd/advance-...