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Researchers at SIC have analysed the skin’s response to exposure to the contact allergen, nickel. They found that the response became more severe with repeated exposures and was likely due to a strong skin-resident T cell response to nickel. academic.oup.com/bjd/advance-...
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Repeated nickel exposure in individuals allergic to the metal leads to increased clinical reactions. The clinical reactions correlate with an accumulation
academic.oup.com
Heterogeneous generation and expansion of epidermal-resident memory T cells in individuals allergic to nickel
LEO Foundation Skin Immunology Research Center (SIC)