To Heme We Bow! Research: anemia; heme & iron trafficking/metabolism; red cell development; parasite-host interactions; drug discovery. Professor: U Maryland; Founder & President: Rakta Therapeutics (website: hamza.umd.edu)
Iqbal Hamza
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This cell-nonautonomous pathway opens a new conceptual framework for understanding erythropoiesis and points toward novel therapeutic targets for #thalassemia and other #anemias where insufficient heme supply limits hemoglobin production.
Red blood cells don't always make their own heme - under stress, they scavange it from neighbors. Our new paper in @ScienceMagazine reveals a cell-nonautonomous heme acquisition pathway essential for erythroid hemoglobinization. #heme #erythropoiesis #anemia
www.science.org/doi/10.1126/...
More about the HFSP recipients are here: bsky.app/profile/hfsp...
Thrilled to share our HFSP grant "Revealing the Hidden World of Heme Proteins in True Colour" has been funded! An international collaboration with Jennifer Ogilvie (Canada), Michel Sliwa (France), & Philipp Kukura (UK) to develop label-free single-molecule imaging of heme transport and trafficking.
Attention scientists from all over the world🙃
44 new #HFSPResearchGrants.
116 New #HFSPAwardees!
From studying sleep to exploring hidden underground ecosystems, #HFSP awardees are pushing the boundaries of life science in unexpected directions! 🧪
Meet the 2026 cohort → bit.ly/4uGmMQ3 #sts
A cell-nonautonomous heme acquisition pathway enables erythroid hemoglobinization under stress https://www.biorxiv.org/content/10.64898/2026.02.10.705195v1
🧪Bacterial DL-peptidases are key in coordindated predetor defenses AND powerful tools for natural product structure elucidation! 🦠✂️
New JACS paper with @pstallforth.bsky.social
@mlakemeyer.bsky.social @en-hxnu-enment.bsky.social & Hertweck labs
@microverse.bsky.social
pubs.acs.org/doi/10.1021/...
