This cell-nonautonomous pathway opens a new conceptual framework for understanding erythropoiesis and points toward novel therapeutic targets for #thalassemia and other #anemias where insufficient heme supply limits hemoglobin production.
🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
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