Postdoc at @molgen.mpg.de in Berlin. Passionate about engineering gene regulation and high-throughput tech dev.
Michael Montgomery
We wrote a perspective "How to build the regulatory genome: a constructionist guide to the cis-regulatory code", out in Development yesterday. Title says it all. Find it here:
journals.biologists.com/dev/article/...
Thanks to co-authors Charles C. Bell, Brendan R. Camellato,
M. Joaquina Delás, Daniel M. Ibrahim, and @michaeltmont.bsky.social
And also to all the participants of the 2024🤨 Company of Biologists meeting that inspired this.
Carl de Boer
Carl de Boer
Had a lot of fun writing this “tools of the trade” highlight for our Variant-EFFECTS technology. Check it out! 🛠️
Very cool work! I'm particularly excited about the integration of multiple models/prediction heads in this approach, given how many aspects of gene regulation likely need to be considered to achieve a specific quantitative design goal.