Introducing AlphaFast 🚀. AF3 is transformative but too slow for large-scale protein design. My students Ben and Jeonghyeon made it 10-100x faster using GPU-accelerated sequence search.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/RomeroLab/al...
What are good places to post an unsolicited manuscript peer review these days? I don't have a blog. I read manuscripts across arXiv, bioRxiv, ChemRxiv, OpenReview, random white papers, journals, etc. Do I dump it on Zenodo, post it here, and send it to the authors?
Horrifying news being confirmed about the state of NSF at the NSF IOS/BIO webinar
A dataset of 40 million protein families and an autoregressive model of protein families. Great to see other protein Atlases popping up after Dayhoff!!
@judewells.bsky.social @dmmiller597.bsky.social
www.biorxiv.org/content/10.6...
Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment.
The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP
jasonjwilliamsny.github.io/grfp2025/
I'm really proud of this work by Jae Kennemur and Yueming Long. #Enzymes rock, with some help from #directed evolution to do chemistry not known in nature (and really hard for humans, too). @caltechcce.bsky.social
pubs.acs.org/doi/10.1021/...
Very excited about our latest all-atom generative model proteina, check out the project page (research.nvidia.com/labs/genair/...) and stay tuned for the code release soon!
Excited to be at the Carolina Biophysics Symposium the next two days to hear and talk about protein eng and design in many therapeutic and green science spaces!! Special thanks to our friends at
@unc-bcbp.bsky.social for organizing! Gonna be an exciting time!
cbs.web.unc.edu
The posting is unfortunately not super clear on this, but please apply if you want to do BioML research, especially around machine learning for molecular biology and bioengineering!
I get sad if there are no applicants with this profile in the pool!
Design stable, folded proteins using only the 10 "ancient" amino acids.
www.biorxiv.org/content/10.1...