Introducing AlphaFast 🚀. AF3 is transformative but too slow for large-scale protein design. My students Ben and Jeonghyeon made it 10-100x faster using GPU-accelerated sequence search.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/RomeroLab/al...
Philip Romero
Design stable, folded proteins using only the 10 "ancient" amino acids.
www.biorxiv.org/content/10.1...
A dataset of 40 million protein families and an autoregressive model of protein families. Great to see other protein Atlases popping up after Dayhoff!!
@judewells.bsky.social @dmmiller597.bsky.social
www.biorxiv.org/content/10.6...
What are good places to post an unsolicited manuscript peer review these days? I don't have a blog. I read manuscripts across arXiv, bioRxiv, ChemRxiv, OpenReview, random white papers, journals, etc. Do I dump it on Zenodo, post it here, and send it to the authors?
