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Super interesting interaction between two esteemed experts of our field. Such important points, especially toward the end where biological reductionism is discussed
4mo
From Mad in Canada: Have you ever been prescribed an antidepressant? And, are you an adult, who lives in Canada? If so, we want to hear from you! Click on the link to fill out this important survey. buff.ly/QPJDsbL
Martin Plöderl
25d
See this detailed thread on our paper. In sum, evidence shows fluoxetine has no meaningful effect. Earlier studies influenced by recency bias. But it is still recommended in clinical guidelines
I agree psychedelics are being pushed now with little regard for the uncertain and potentially negative consequences of repeated use
Welcome to the world of "pure" biological psychiatry "MDD is increasingly understood as a disorder of dysregulated neuroplasticity rather than solely of neurotransmitter imbalance" www.biorxiv.org/content/bior... @padbergthorsten.bsky.social @joannamoncrieff.bsky.social @mad-in-america.bsky.social
Good commentary on the issue!
It was great that BBC radio 4 covered the harmful effects of finasteride, including persistent sexual dysfunction. More attention is needed to the fact that SSRIs and other antidepressants cause similar, potentially devastating effects. www.bbc.co.uk/sounds/play/...
🔥 Finally, our commentary on the problematic harm benefit ratio of escitalopram to treat pediatric generalized anxiety disorder is published. It took about 2 years and several rejections. With @floriannaudet.bsky.social @joannamoncrieff.bsky.social @markhoro.bsky.social and John Warren 🧵 below