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Happy to share a new preprint from our lab, uncovering "spooky action at a distance" - for RNA Polymerase II: www.biorxiv.org/content/10.6...
Online Now: Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains Online now:
This fun project was driven by the talented and rigorous Alex Gillis @cftbla.bsky.social, in wonderful collaboration with Ana Tufegdžić Vidaković's @anatv.bsky.social lab! @singmolsci.bsky.social @unswrna.bsky.social
A purpose built solution to Australia’s biomedical funding crisis….. release the #MRFF = invest in our future scientists & their discoveries. #DiscoveriesNeedDollars www.smh.com.au/politics/fed...
6mo
What happens when you suddenly remove half of an essential enzyme from cells? 🤔 We watched in real-time as cells deploy multiple backup strategies to buffer against changes in RNA Pol II abundance. Our lab's new preprint 👇 bit.ly/4pyPgax
AEpiA 2026 early bird registration open now! Calling all epigenetics researchers, let’s meet, share, and connect! 14–16 Sep | Adelaide 🇦🇺 | National Wine Centre Register: 2026aepia.com.au/registration Abstracts: 2026aepia.com.au/abstracts #AEpiA2026 #Epigenetics #Chromatin
🌟 𝐈𝐧𝐭𝐫𝐨𝐝𝐮𝐜𝐢𝐧𝐠 𝐄𝐌𝐂𝐑 𝐌𝐢𝐧𝐢 𝐒𝐲𝐦𝐩𝐨𝐬𝐢𝐮𝐦 𝐂𝐚𝐫𝐞𝐞𝐫 𝐏𝐚𝐧𝐞𝐥𝐥𝐢𝐬𝐭 – 𝐃𝐫 𝐋𝐮𝐤𝐞 𝐈𝐬𝐛𝐞𝐥 🌟 We’re excited to spotlight Dr Luke Isbel, one of our inspiring career development panellists for the upcoming Australasian Epigenetics Alliance 𝐄𝐌𝐂𝐑 𝐌𝐢𝐧𝐢 𝐒𝐲𝐦𝐩𝐨𝐬𝐢𝐮𝐦! aepia.org.au/emcr-symposium
🎉 𝙒𝙝𝙖𝙩 𝙖 𝙙𝙖𝙮! 🎉 On Thursday we held our inaugural EMCR Mini Symposium, bringing together six in-person nodes plus online attendees from across Australasia. It was fantastic to see our community come together to share science, build connections, and finish 2025 strong. #EMCR #AEpiA #epigenetics
3mo
DNA is scattered with obstacles that stall RNA polymerase II (Pol II) and block the production of full-length transcripts. Two mechanisms are known to resolve stalled Pol II: transcription-coupled nuc...
www.biorxiv.org
5mo
8mo
Stalling of elongating Pol II triggers Ser7 phosphorylation in trans to drive transcription recovery
5mo
4mo
8mo
6mo
The Asia RNA Club Symposium will be happening in Seoul in Nov 3-5, bringing together RNA scientists from the Asia-Pacific region. Excellent speakers and a great opportunity to connect! Abstract submission by Sept 5 asiarnaclub.org
Optimised nanobody-based quenchbodies are developed through rational design and in vitro evolution, enabling improved protein detection with up to 2.4-fold fluorescence increase @haiboyu.bsky.social @lisannes.bsky.social @molecularhorizons.bsky.social www.nature.com/articles/s42...
RNA polymerase II (Pol II) abundance and transcriptional output are coordinated across diverse conditions to maintain mRNA homeostasis. To determine whether Pol II acts as a limiting factor for transc...
bit.ly
Hierarchical buffering of cellular RNA polymerase II pools maintains transcriptional homeostasis
Ana Tufegdzic Vidakovic
10mo
Jun 19, 2025