science writer- biology, medicine, chemistry, engineering- for universities, institutions, foundations, alumni mags. also mom to 3, and occasional microfiction author.
Sarah CP Williams
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A microscope at @gladstoneinst.bsky.social is on the search for new Parkinson's treatments. It designs its own experiments, runs thousands simultaneously on individual cells, learns from the results, and repeats-- without guidance from scientists. gladstone.org/news/how-ai-...
For the first time, a vaccine reliably produced broadly neutralizing HIV antibodies in every animal tested. @scripps.edu & @ki.se researchers targeted the apex of HIV's spike, a region nearly identical across hundreds of thousands of strains. www.scripps.edu/news-and-eve...
Scientists thought DNA wrapped in nucleosomes was either locked away or accessible, on or off. "It's more like a volume dial," says @gladstoneinst.bsky.social's Vijay Ramani. An AI tool described in @nature.com found 14 nucleosome states- a new layer of genomic grammar. gladstone.org/index.php/ne...
Precise bacterial genome editing has been largely stuck in E. coli. Scientists at @gladstoneinst.bsky.social just changed that, showing that their retron-based editing tools work across 15 diverse species of bacteria. gladstone.org/news/univers...
Carbon capture and CO₂ conversion are usually two separate, expensive steps. @uchicagopme.bsky.social and Argonne scientists combined them into one system that works efficiently even under messy, real-world flue conditions. pme.uchicago.edu/news/researc...
How does the brain drain its waste? A new method developed at @gladstoneinst.bsky.social maps the routes proteins takes out of the brain. The result: unexpected biology, and new insight into how disease disrupts the brain's cleanup system. gladstone.org/news/mapping...
ChatGPT learned language from millions of texts. @gladstoneinst.bsky.social's Geneformer learned the language of human genes from 100 million cells. Now, it can predict which genes to target to fix diseased cells. My latest for a Gladstone series on science & AI: gladstone.org/news/how-ai-...
Brain immune cells stay chronically overactivated in Alzheimer's, destroying synapses. @scripps.edu scientists traced that inflammation to a single chemical modification on one protein. Blocking the modification protects synapses in mice. www.scripps.edu/news-and-eve...
At @columbiamed.bsky.social, scientists are no longer betting everything on a single, simple explanation for Alzheimer's. Instead, they are mapping the subtypes, the way oncologists once did for cancer, to finally develop targeted treatments. www.vagelos.columbia.edu/about-us/col...
Ventricular fibrillation moves so fast that sending cardiac data to a remote server takes too long to save a life. A new skin-like AI computing patch from @SihongWang_UChi @UChicagoPME runs the analysis in milliseconds, directly on the body. pme.uchicago.edu/news/researc...
A new study upends long-held view about how DNA is stored, explaining how subtle shifts in gene activity contribute to cancer, aging, and other complex diseases.
Gladstone scientists have developed a thinking microscope that can conduct its own experiments, with the ultimate goal of treating neurodegenerative diseases.
The new approach, developed by UChicago PME and Argonne National Laboratory researchers, offers a streamlined and cost-effective pathway toward decarbonization.
Approaching Alzheimer’s from every angle, Columbia scientists are finding unexpected inroads to this complex disease and forging paths to new treatment possibilities.
A new fabrication method enables large-scale stretchable transistor arrays to run AI algorithms directly on the body, without transmitting data to an external computer
