🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
Excited to see our work published on @cp-immunity.bsky.social.
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
www.cell.com
Long-term consumption of diets high in fats has detrimental impacts on the immune
system, but the window necessary for initiating these effects is unclear. In this
issue of Immunity, Xiong et al. demo...
Interesting approach from Chao Zhong’s group to dissect the role of RORgt in activated ILC3 highlighting its essential function in driving HB-EGF expression, rather than IL-22.
www.cell.com/cell-reports...