Interesting approach from Chao Zhong’s group to dissect the role of RORgt in activated ILC3 highlighting its essential function in driving HB-EGF expression, rather than IL-22.
www.cell.com/cell-reports...
Li et al. show that RORγt, the ILC3 master regulator, still plays a crucial role during
the ILC3 activation phase. Although it is dispensable for ILC3 maintenance and their
IL-22 production, it is req...
