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Our most recent paper "Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility" is now out in @jcb.org! Check it out here: rupress.org/jcb/article/...
I'm happy to share a review that our lab put together on innate immune responses to Rickettsia. One interesting tidbit - different Rickettsia species have distinct interactions with xenophagy, where some species co-opt ubiquitylation, while others avoid it! www.sciencedirect.com/science/arti...
1mo
1mo
Excited to share our latest work from first author Patrick Woida. Using a novel surface display platform for expression of split TurboID, we discovered that CYLD is recruited to the Listeria surface via the effector InlC and that it supports cell-to-cell spread www.biorxiv.org/content/10.6...
3mo
Over 10 species of Rickettsia cause serious human disease across the globe, including deadly spotted fever and typhus. These arthropod-borne microbes …
www.sciencedirect.com
Innate immune responses to Rickettsia: emerging themes and contrasts between species
Check out our latest paper from first author Allison Scott using a powerful enrichment strategy to enable transcriptional profiling of the early stages of a rickettsial infection
With CauloCon coming up in a few weeks, we are excited to share with you the schedule for the upcoming meeting! There will be 3 keynotes and 26 short talks over three days. You can see more information at caulocon.com
Matthew Welch
Thomas P200 Burke
🚨 New preprint: GATO-seq did it again! ELOF1 is the missing promoter-proximal factor that confers RNA Pol II resistance to TFIIF. Including ELOF1, DSIF, and NELF in GATO-seq reactions recapitulates promoter-proximal pausing in vitro at physiological conditions for the 1st time. tinyurl.com/ELOF1
Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00): for Individuals whose final due date was September-November 2025 and January-March 2026. As always, reach out to your PO/IC contact to discuss. grants.nih.gov/grants/guide...
How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism: merenlab.org/2026/04/15/u...
5mo
www.biorxiv.org
3mo
14d
Interested in genetically encodable inhibitors of your favorite biomolecular condensate? Excited to announce our latest work, w/ Jibin Sadasivan, Gene-Wei Li, & Lindsay Case, on protein fragments as generalizable regulators of phase separation. (1/n) www.biorxiv.org/content/10.6...
4mo
1mo
Video
Becky Lamason
1mo
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00) NOT-OD-26-021. OD
grants.nih.gov
NOT-OD-26-021: Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00)
Unfalsifiable by Design: A Year of Trying and Failing to Reproduce a Human Microbiome and Autism Study
The myth of open data, reproducibility, responsibility, and accountability in science, and your role in it
merenlab.org
Becky Lamason
I-75 Scientist
A. Murat Eren (Meren)
Caulocon
Roberto Vázquez Núñez
Hybrid capture RNA-seq defines temporal gene expression in Rickettsia https://www.biorxiv.org/content/10.64898/2026.01.04.697603v1