An initial idea from our previous work turned into 💣💥🔥🔥🔥: Pioneering activity of WNT-beta catenin - here, we said it: look at the preprint and let us know your thoughts!!
Led by Tamina Weiss, @annanordin.bsky.social , @claudiocantu81.bsky.social at @liu.se
Pierfrancesco Pagella
FASTEN YOUR SEATBELTS:
Tamina Weiss, inspired by previous data from @ppagella86.bsky.social
found that beta-catenin is more than an adaptor protein downstream of #WNT
It is an orchestrator that scouts and opens enhancers for transcriptional activation
@biorxivpreprint.bsky.social
Claudio Cantù
Enhancer pioneering activity of Wnt/β-catenin signaling https://www.biorxiv.org/content/10.64898/2026.06.12.731851v1