Open access journal highlighting new discoveries, technical developments and policies in basic, translational, and clinical cancer research. Part of FEBS Press.
moloncol.org
Molecular Oncology
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π‘ Can cancer be stopped before it starts?
In a Viewpoint, researchers from the
@charlesswanton.bsky.social
lab discuss cancer interception, to prevent cancer before it develops. Could this be the next frontier in oncology?
π febs.onlinelibrary.wiley.com/doi/10.1002/...
#CancerPrevention #EACR
Our latest issue is out! π£
π We are pleased to present manuscripts showcasing a breadth of topics from insights into tumour evolution, new approaches to intercept cancer before it develops, and novel therapeutic targets in glioblastoma.
π Full issue: febs.onlinelibrary.wiley.com/toc/18780261...
π New Review for your weekend reading!
Liquid biopsy epigenetics: establishing a molecular profile based on cell-free DNA
π buff.ly/4a4AmPZ
#Epigenetics #LiquidBiopsy #CellFreeDNA #cfDNA
π¬ Curious about mechanisms driving melanoma progression and metastasis?
The Wolnicka-GΕubisz lab identified RIPK4 as a regulator of melanoma cell adhesion and metastasis, highlighting its role as a modulator of tumour plasticity. π
π Full text: febs.onlinelibrary.wiley.com/doi/10.1002/...
π‘ Join us in congratulating Michalis Gounis @gounismichalis.bsky.social postdoctoral researcher from @turkubioscience.bsky.social for winning the Best Oral Talk FEBS Molecular Oncology prize πat FEBS 2026 Advanced Course on Tumour microenvironment in Fodele, Greece. Well done! π
#FEBS #FEBSPress
β‘οΈ May Issue is out β
In support of #Melanoma and Skin Cancer Awareness Month, we present a collection of articles focused on melanoma.
πCover: Melanoma-secreted peroxidase enables immune escape by binding the NKG2D receptor on NK cells by Hsu-Min Sung et al. - pp 1161-1184.
π buff.ly/TQtHfXU
π‘Interested in PD-L1 regulation in melanoma?
π A new study from the Annemiek van Spriel and colleagues identifies TSPAN4 as a negative regulator of PD-L1 in melanoma, uncovering a new layer of immune checkpoint regulation.
π Read the full manuscript: febs.onlinelibrary.wiley.com/doi/10.1002/...
π‘This week we highlight a study from the Jochen Utikal lab at @dkfz.bsky.social.
π§¬Authors provide new insights into overcoming therapy resistance in melanoma, suggesting ERRFI1 as a potential target for treatment of metastatic melanoma.π
β‘οΈ Full text: febs.onlinelibrary.wiley.com/doi/10.1002/...
Weβre thrilled to reveal the winners of the Molecular Oncology Writing Contest 2026! π
π Muhammad Habiburrahman
π₯ Alyssa Paparella
π₯ Ihsaan Jama
β‘οΈ Read their essays on: febs.onlinelibrary.wiley.com/hub/journal/...
π Congratulations! Way to go!
#SciComm #FEBS #WritingCommunity #OpenAccess
β‘οΈ What drives the anticancer activity of plecstatin in hepatocellular carcinoma?
π Researchers from the gregorlab.bsky.social at @imgprague.bsky.social identify plectin as key target of this metallodrug, dissecting its anti-tumor activity.
π Full text: febs.onlinelibrary.wiley.com/doi/full/10....
Molecular Oncology
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Molecular Oncology
<em>Molecular Oncology</em> is an open access FEBS journal covering basic, translational, and clinical cancer research, as well as cancer diagnosis, prevention and care.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD-L1 interactome of melanoma cells. TSPAN4 negatively regulates PD-L1 expression and lateral mobility by limit...