Original work here ⬇️, led by the inimitable Lorenzo Brunetti and Michael Gundry. This work became foundational in the field.
Rotation PhD student @emiliedevet.bsky.social in our lab made the Dish soap protocol work (on the first attempt) for a nuclear target with Dawn (the US version of dreft/fairy ) and thereby extended the dish soap protocol to a version for across the atlantic 🤩 @tothovalab.bsky.social #hemesky
Brunetti et al. show that specific loss of NPM1c from the cytoplasm leads to downregulation
of HOX genes and differentiation in NPM1 mutant AML. Blocking NPM1c nuclear export
by XPO1 inhibition reduce...
Come see our presidential keynote presentation from FOCIS President Ignacio Anegon in Salon 8! 📣📣
#Focis2026
Dorien Pastoors
🚨 Don’t miss the upcoming joint FOCIS & IUIS Virtual Symposium
💡 Immune-Mediated Inflammatory Diseases, New Mechanisms, and Therapeutic Options
📆 Thursday, May 7, 2026 | 4:00 - 5:30 PM (London); 10:00 - 11:30 AM (Chicago)
Register now: zurl.co/7MGet
Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation https://www.biorxiv.org/content/10.64898/2025.12.10.693159v1
