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Now online! Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
3mo
Cell - a Cell Press journal
Online now: B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells
4mo
Cost of being female lead/corresponding author in biomedical sciences: "[T]he median amount of time spent under review is 7.4%–14.6% longer for female-authored articles than for male-authored articles" even in disciplines where women well-represented. #AcademicSky journals.plos.org/plosbiology/...
Yesterday we had the privilege of contributing to a RoundTable in Whitehall on "Women in Research" - the future, barriers & potential solutions to address many systemic issues. We're excited to see how these conversations continue @laurawolz.bsky.social @carterlj.bsky.social @pallettlab.bsky.social
4mo
3mo
Immunity
Prof Jenny Rohn
Thanks to @iansample.bsky.social at the Guardian for covering the devastating funding cuts that are being proposed for UK (astro)physics, and the dire impact these would have on young researchers. Will UKRI/STFC reconsider? Will the UKGov step in?🤞👩‍🔬🧪⚛️🔭 www.theguardian.com/science/2026...
Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more. 📅 Abstract deadline: Monday 29 June 2026 🎟️ Register early to save! Learn more: vist.ly/54ad6
4mo
29d
Carers In STEMM
No matter where they live, kids cooperate according to their community’s social norms by middle childhood. Learn more in #ScienceAdvances: https://scim.ag/4r0Rxga
Women are underrepresented in academia, especially in STEMM fields, at top institutions, and in senior positions. This study analyzes millions of biomedical and life science articles, revealing that f...
journals.plos.org
Biomedical and life science articles by female researchers spend longer under review
****2-NBDG does not measure glucose uptake**** Just your regular reminder of this fact 😁. See the rigorous proof of this fact in @lindavsinclair.bsky.social 2020 paper. This paper was 6 years ago!! Stop using 2NBDG to measure glucose uptake already 🙄 pmc.ncbi.nlm.nih.gov/articles/PMC...
Human pancreatic cancer cells sense specific components of the ECM to fine-tune their autophagy flux levels, conferring the ability to coordinate proliferation, survival, and responsiveness to chemotherapy. Targeting ECM sensing may turn this ability into a therapeutic opportunity.
dlvr.it
Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
Postdoc alert in spatial biology! Building upon our previous work with MSI cancers (e.g. de Vries et al, Nature, 2023), the Voest Group at the NKI is hiring a (fully funded) postdoctoral fellow with strong expertise in spatial cancer biology. Learn more / apply here: www.nki.nl/careers-stud...
On the difficult situation of young UK researchers 🧪🔭 Thanks @fionamcintyre.bsky.social and @isaacbarbosa1.bsky.social for the interview & excellent article. #stfc #ukri #saveSTFC @ukri.org UKRI funding changes ‘pushing junior researchers abroad’ www.researchprofessionalnews.com/rr-news-uk-r...
4mo
British Society for Immunology
Astronomer Royal for Scotland | Catherine Heymans
4mo
3mo
4mo
UK’s research funding body says best scientists are taking posts overseas due to lack of job stability at home
www.theguardian.com
UK ‘could lose generation of scientists’ with cuts to projects and research facilities
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose ...
pmc.ncbi.nlm.nih.gov
Single Cell Glucose Uptake Assays: A Cautionary Tale
Science Magazine
B cells transiently increase interleukin (IL)-2 receptor expression upon activation. Gauthier et al. examine the B cell-intrinsic role of IL-2 and define an IL-2-MAF axis that promotes the differentiation of CD25+ age-associated B cells toward a regulatory, IL-10-producing phenotype that is protective in neuroinflammation.
dlvr.it
B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells
Joris van de Haar, MD, PhD
Lucien Heurtier
David Finlay
🔊 Calling UK early career researches in astro, particle & nuclear physics. Please sign this open response to the proposed cuts at STFC ⚛️🧪🔭 "Protecting the UK's reputation as a science superpower requires not only investment, but continuity, confidence, and people" ✍️ ecr-openletter-stfc.github.io
4mo
Astronomer Royal for Scotland | Catherine Heymans
Children’s cooperative behaviors and norms develop along distinct cultural pathways shaped by local norms.
scim.ag
The emergence of cooperative behaviors, norms, and strategies across five diverse societies
Computational Postdoc Voest Lab (fully funded) — Spatial Decoding of Unconventional Antitumor Immunity in Colorectal Cancer
www.nki.nl
Computational Postdoc | Netherlands Cancer Institute
Disruptions to core funding streams raise fears for a “generation” of early career researchers
UKRI funding changes ‘pushing junior researchers abroad’ - Research Professional News
www.researchprofessionalnews.com
An excellent open-letter enumerating the dangers to early career researchers and then wider society of proposed changes to UK science funding ecr-openletter-stfc.github.io Early-career researchers may like to add their signatures 🧪⚛️🔭 #AcademicSky #UKpol
4mo
ecr-openletter-stfc.github.io
Early Career Researchers Response to UKRI Investment Approach
Christopher Berry