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Our June issue is live! 🎉 www.nature.com/nmeth/volume... On the cover, an absolutely gorgeous image of neurites and mitochondria in a brain organoid, captured using the MOSAIC microscope. Paper here: www.nature.com/articles/s41...
An Analysis evaluated the effect of pretraining dataset size and diversity on the performance of single-cell foundation models. @alandenadel.bsky.social @nfusi.bsky.social @lcrawford.bsky.social @avapamini.bsky.social www.nature.com/articles/s41...
A lightweight head-mounted multiplane microscope allows simultaneous imaging of 1800 neurons in freely moving mice, sampled over weeks. www.nature.com/articles/s41...
Also read this month's Editorial which (re)introduces the Points of View. www.nature.com/articles/s41...
Read the associated Research Briefing here: www.nature.com/articles/s41...
m6A-ARTR-DBiT offers a spatial assay to profile the distribution of m6A across the transcriptome in intact tissue sections. www.nature.com/articles/s41...
OrthoFinder v3: a tool for phylogenetic orthology inference with boosted accuracy and scalability for massive datasets. @lauriebelch.bsky.social @stevenkelly.bsky.social @jonathancholmes.bsky.social @yiliu88.bsky.social www.nature.com/articles/s41...
We are very excited to bring back our popular Points of View column, written by @helenajambor.bsky.social! Check out her first column in our July issue about the usage of color scales in scientific figures. www.nature.com/articles/s41...
And read the associated News & Views here: www.nature.com/articles/s41...
A Perspective discusses the use of external validation using independent datasets for improving human neuroimaging studies. @dscheinost.bsky.social @matt-rosenblatt.bsky.social www.nature.com/articles/s41...
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The performance of single-cell foundation models is dependent on many factors. This study assesses the effect of the pretraining dataset’s size and diversity, revealing potential challenges in pursuin...
www.nature.com
A lightweight head-mounted multiplane microscope allows simultaneous imaging from >1,800 neurons spread across the cortical layers in freely moving mice performing complex behavioral tasks, sampled...
www.nature.com
Evaluating the role of pretraining dataset size and diversity on single-cell foundation model performance - Nature Methods
Simultaneous two- and three-photon multiplane imaging across cortical layers in freely moving mice - Nature Methods
Points of View, anew - Nature Methods
This month, we reintroduce the Points of View column, with updated practical advice for visualizing scientific data.
www.nature.com
The advantages of training foundation models for single-cell datasets on large (tens of millions of cells) datasets have not been systematically tested. We evaluated the role of the size and diversity...
www.nature.com
Scaling up training dataset size for transcriptomic AI models is much pain with little gain - Nature Methods
m6A-ARTR-DBiT offers a spatial assay to profile the distribution of N6-methyladenosine (m6A) across the transcriptome in intact tissue sections.
www.nature.com
The updated OrthoFinder v3 software boosts accuracy and scalability in phylogenetic orthology inference with massive and diverse datasets.
www.nature.com
Spatially resolved m6A profiling using m6A-ARTR-DBiT - Nature Methods
OrthoFinder: improved phylogenetic orthology inference with enhanced accuracy and scalability - Nature Methods
The color palette viridis is replacing rainbow color schemes in scientific figures, for good reason.
www.nature.com
The m6A-ARTR-DBiT technique allows the spatial profiling of m6A mRNA modifications.
www.nature.com
This Perspective promotes the use of external validation using independent datasets for human neuroimaging studies.
Color scales and the birth of viridis - Nature Methods
Spatial epitranscriptomics: from Cinderella to queen - Nature Methods
External validation improves generalizability, replicability and reproducibility in predictive models for neuroimaging - Nature Methods
www.nature.com
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