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A little late to share, but still thrilled 🤗! What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters. When forces unite… 👇👇👇
11mo
Emilie Brasset
New online: Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Jun 17, 2025
Nature Structural & Molecular Biology, Published online: 17 June 2025; doi:10.1038/s41594-025-01584-8The authors reveal that, in fruit fly ovaries, the protein Rhino is guided to specific regions of the genome by a combination of two histone modifications, enhancing understanding of how cells protect their DNA from harmful virus-like elements.
go.nature.com
Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Nature Structural & Molecular Biology