We are very excited that our work on Torsins, dystonia and NE membrane fusion is out on bioRxiv: doi.org/10.1101/2025...
Fantastic collaboration with Madhav Jagannathan and the labs of Gautam Dey and Stefano Vanni!
We are very excited that our work on Torsins, dystonia and NE membrane fusion is out on bioRxiv: doi.org/10.1101/2025...
Fantastic collaboration with Madhav Jagannathan and the labs of Gautam Dey and Stefano Vanni!
DYT1 early-onset dystonia is a severe, incurable disorder of the central nervous system caused by mutations in the gene encoding Torsin1A (Tor1A, DYT1). Torsins are ER-resident AAA+-ATPases implicated...
doi.org
DYT1 early-onset dystonia is a severe, incurable disorder of the central nervous system caused by mutations in the gene encoding Torsin1A (Tor1A, DYT1). Torsins are ER-resident AAA+-ATPases implicated...
Publication by the Kutay lab with first author Claudia Gafko "Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors" in BMC Biol
nccr-rna-and-disease.ch/news/article...
@kutaylab.bsky.social
@ethz.ch
☕ @kutaylab.bsky.social & co identify #lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether #heterochromatin to the envelope. Deletion of these proteins causes changes in 3D #genome organization, gene expression and cell fate determination.
bit.ly/4aPkNBc
Video
Lewis et al. identify lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether heterochromatin to the envelope. Deletion of these proteins causes changes in 3D ge...
We are delighted by the publication of our work identifying human LBR and LAP2 as key heterochromatin tethers at the nuclear envelope.
Their loss massively changes 3D chromatin organization, and causes defects in epigenetic maintenance and cell fate determination.
doi.org/10.1038/s415...
We are delighted by the publication of our work identifying human LBR and LAP2 as key heterochromatin tethers at the nuclear envelope.
Their loss massively changes 3D chromatin organization, and causes defects in epigenetic maintenance and cell fate determination.
doi.org/10.1038/s415...
Nature Cell Biology
Lewis et al. identify lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether heterochromatin to the envelope. Deletion of these proteins causes changes in 3D ge...
Lewis et al. identify lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether heterochromatin to the envelope. Deletion of these proteins causes changes in 3D ge...
