So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇
www.science.org/doi/10.1126/...
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
Thank you
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...
Many pathogens that infect wild plants are close relatives of crop pathogens. Important model systems for studying plant diseases. Check out the special issue on wild plant pathosystems published in the Philosophical Transactions B: royalsocietypublishing.org/rstb/issue/3...
Thrilled to share our paper now out in Nature Plants 🎉
We developed a genome-host association (GHA) approach to study pathogen adaptation directly from field metadata by using the originating host cultivar as phenotype.
www.nature.com/articles/s41...
Super excited to see our work on the Pm3e NLR that recognises two structurally diverse AVR effectors from powdery mildew out in @natcomms.nature.com
Congratulations to @lukas-kunz.bsky.social, Beat Keller, and everyone involved!
Check it out ➡️https://www.nature.com/articles/s41467-026-72199-w
A very interesting read:
The wheat NLR Pm3e provides broad-spectrum resistance against powdery mildew. Here, the authors show that Pm3e recognizes two structurally unrelated effector proteins and that its range can be further...
www.nature.com
This study introduces genome–host association (GHA), leveraging natural epidemics to map the genetic landscape of host adaptation in the pathogen Zymoseptoria tritici. Applied to 832 wheat fungal stra...
We have an open PhD position in our Mol. Biochemistry of Plant-Microbe Interactions Lab Saurlab.com. Please see details below, share and consider applying. jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de
Cecile Lorrain
Lukas Kunz
Marion C. Müller
As seen on @biorxivpreprint.bsky.social: our story on how the dreaded late blight pathogen hijacks a helper NLR pathway is now out in its final form! 🎉
Meet AVRcap1b: the two-faced effector 🧵👇
www.science.org/doi/10.1126/...
A plant pathogen effector suppresses an activated helper NLR via a host ENTH domain–containing protein, NbTOL9a.
#TansleyInsight: Entanglement of plant immunity and endomembrane trafficking revealed by plant–powdery mildew fungal interactions
Thordal-Christensen et al.
👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience @sohini-d.bsky.social
📢 EffectorGeneP is finally here! Stop missing small, single-exon or orphan genes from your favourite pathogen genome. Current tools only annotate 15%-78% of effector genes, EffectorGeneP finds 95% - including the large AvrSr26 family in stem rust. #Bioinformatics 📖 www.biorxiv.org/content/10.6...
www.biorxiv.org
Mauricio Contreras
New Phytologist
Jana Sperschneider
Host specificity in cereal rust fungi is mediated by a conserved glycoside hydrolase family https://www.biorxiv.org/content/10.64898/2026.05.20.726508v1
