Distal and proximal transcriptional activation may not be so different - check out the latest pre-print from @eliasfriman.bsky.social
Very happy to have contributed a small part and seen this story develop!
Giovanna Weykopf
Is distal gene activation by enhancers inherently different from promoter-proximal activation? We propose not. But both cohesin and cooperativity are important aspects of how transcription is affected. Happy to share our recent preprint (thread below) 1/
www.biorxiv.org/content/10.6...