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Distal and proximal transcriptional activation may not be so different - check out the latest pre-print from @eliasfriman.bsky.social Very happy to have contributed a small part and seen this story develop!
1mo
Please help me find a great student! I have a PhD position in my lab in Munich, looking at the dynamics of DNA damage and repair from chemotherapy: jobs.dkfz.de/en/jobs/1686... The application deadline is 02.07.26 @dkfz.bsky.social @lmu-klinikum.bsky.social
A fascinating thread highlighting compelling investigations of the effects (or lack thereof) of distal vs proximal enhancer activation of promoters. The ability for elements to promote transcription from megabases away has always astounded me. Excellent work - with clearly more to do!
1h
1mo
Giovanna Weykopf
Check out the🧵below on the latest pre-print from @eliasfriman.bsky.social I am really glad to have had the opportunity to contribute to this exciting project! ✨
1mo
Craig Anderson
Hannah Josefine Jüllig
Anthony Dornan
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇
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